Postdoctoral Researcher Position - Llorente Lab
Job Description
Postdoctoral Researcher Position – Llorente Lab
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The Llorente Lab within the Division of Gastroenterology, Department of Medicine at UC San Diego, is hiring a Postdoctoral Researcher to join our funded NIH research projects.
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Our research focuses on understanding the mechanisms that regulate intestinal homeostasis, including interactions among the intestinal epithelium, microbiome, and immune system, and how these processes influence liver disease, including metabolic dysfunction-associated steatotic liver disease (MASLD) and alcohol-associated liver disease (ALD), as well as substance use disorders.
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Our projects investigate the gut–liver axis and gut–vagus–brain axis using preclinical animal models and patient-derived samples. We employ cutting-edge approaches, including metabolomics, metagenomics, single-cell RNA sequencing, spatial transcriptomics, and intestinal and liver organoid cultures, to uncover mechanisms underlying disease and identify novel therapeutic strategies.
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A major goal of our research is translational: to identify and develop innovative therapeutic approaches for liver disease and substance use disorders, including bacteriophage-based therapies and other microbiome-targeted interventions.
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Qualifications
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Applicants must have a PhD in neuroscience, gastroenterology, biochemistry, biology, microbiology, pharmacy, immunology, or another biomedical science discipline.
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We particularly encourage applications from candidates with experience or strong interest in:
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- Neuroscience
- Biochemistry
- Microbiology and microbiome research
- Immunology
- Biomedical research
- Liver disease research
- Substance use disorders research
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Experience with mouse models, nodose ganglion isolation, bacteriophage therapy, FACS/flow cytometry, single-cell multiomics, or spatial transcriptomics is advantageous.
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The ideal candidate will be highly motivated, intellectually curious, creative, and passionate about science, with a strong record of research productivity and a desire to pursue innovative and translational research.
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Application
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Interested applicants should submit the following documents:
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- CV or resume, including contact information for 2–3 references
- Cover letter describing your research experience, interests, and motivation for joining the Llorente Lab
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Please send application materials directly to Dr. Llorente at allorenteizquierdo@health.ucsd.edu.
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We look forward to hearing from enthusiastic and motivated scientists interested in advancing our understanding of the gut–liver and gut–brain axes and developing new therapeutic strategies for human disease.