Scientist III -Antibody Purification (AKTA)
Job Description
Job Description
Job ID: 353
Scientist III
Contract: 6 Months (Renewable)
Location: Alameda, CA
Compensation: Up to $77/hr. W2
Shift: 8AM-5PM PST Duration: 6 Months
Possibility to extend or convert: Yes, possible extension
Interview Process: 2 rounds; 30-minute virtual interview with manager, followed by a 2 hour on-site interviews with 2 additional interviewers
Top Skills:
- Experienced and knowledgeable with demonstrated proficiency and proven track record in therapeutic monoclonal antibody purification using AKTA and antibody characterization.
- Strong AKTA experience
- Experience purifying therapeutic monoclonal antibodies
- Prior experience in a discovery-stage biotech or pharmaceutical organization. Candidates with only academic research experience are likely not competitive
Strong Plus:
Experience with protein and antibody characterization, including SEC-HPLC
Job Description:
ESSENTIAL DUTIES AND RESPONSIBILITIES:
- Purify recombinant antibodies, bispecific antibodies and recombinant proteins using industry-standard practices to support the group’s discovery and pipeline efforts.
- Be proficient in different purification technologies (e.g. ProA, CH1, and IEX) to support antibody and protein purification using AKTA systems and HT purification processes.
- Provide scientific input on protein/antibody production, purification, and characterization to support the discovery and preclinical development of biotherapeutic candidates.
- Play a role in assessing protein structure/function and protein quality as applied towards the evaluation of biologics for developability and large-scale manufacturing.
- Comply with company health and safety policies and general laboratory practices.
Education:
Bachelor’s degree in related discipline and at least 7 years of related experience or
Master’s degree in related discipline and 4-5 years of related experience or
PhD + 0-3 years of related experience
EXPERIENCE:
· Experienced and knowledgeable with demonstrated proficiency and proven track record in therapeutic monoclonal antibody purification using AKTA and antibody characterization.
· Experience writing summaries, reports, analyzing, interpretating and presenting scientific data/results to internal collaborators.
· Knowledgeable in the purification of proteins and antibodies using various modes of chromatography (affinity, size-exclusion, ion-exchange and HIC).
· Knowledgeable in protein and antibody characterization suitable to ensure developability and large-scale production using efficient and streamlined processes.
Work Location: In person
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